Ph Level Analysis Study on Patient Mortality in Hospitals

Acidosis Mortality Chronic Disease pH Value

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January 23, 2025

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Chronic diseases are significant health issues classified by WHO into communicable and non-communicable types. Acid-base balance disorders are suspected to exacerbate disease severity, increase mortality risk, and potentially result in death. This research aimed to investigate the relationship between blood pH levels and mortality among hospitalized patients. A cross-sectional observational analysis was employed using medical record data from patients diagnosed with heart disease (CHF, IHD), diabetes mellitus (DM), stroke (ischemic and hemorrhagic), pulmonary disorders (pneumonia, tuberculosis), kidney function disorders (CKD), and sepsis (septic shock). Arterial blood gas analysis (ABG) data were collected from Jogja Hospital patients during 2022-2023. The research involved 194 subjects, categorized into two groups: deceased and surviving patients. Statistical analysis using a t-test compared the average pH levels between the groups. The findings revealed that the average pH level in the living group was 7.325, whereas the deceased group had a more acidic pH of 7.25, with a statistically significant difference (p<0.05). Severe acidosis, often caused by hyperlactatemia, was associated with organ dysfunction and increased mortality risk, particularly among sepsis patients. The research highlights that acidic blood pH, indicative of acidosis, is linked to various etiologies and a poor prognosis. These results underscore the importance of monitoring and managing acid-base balance disorders to improve patient outcomes and reduce mortality.